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Female Issues
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Hormones: 
Several studies have analyzed hair follicle chemistry and serum (blood) chemistry to determine differences in androgen, testosterone, dihydrotestosterone, lipases, 5alpha-reductase, etc. levels between men and women, men with and without acne and women with and without acne.  While these tests have determined males have more testosterone than females, there seems to be no "smoking gun" regarding irregularities between those with or without acne, with one important exception.

Females with acne have significantly higher serum androgen levels than their female counterparts without acne.  Since androgens target the skin, it would be logical that higher serum androgen levels would translate into higher skin levels and folliclular androgen levels.  The above research was published less than two years ago and we are unable to find subsequent research to confirm these findings, at this time.

Research on SAHA syndrome [seborrhea, acne, hirsutism (excessive body or facial hair) and alopecia (the loss of hair)] in women reveals higher levels of dihydrotestosterone within the skin and confirms that in many cases women with acne (who are known to have higher serum androgen levels) also have higher skin and follicle androgen levels.  Therefore, effective treatment of female acne must include a comprehensive method of down-regulating testosterone and dihydrotestosterone.

It is noteworthy that seborrhea, acne and alopecia can all be related to classic systemic zinc deficiency.  Zinc deficiency in the skin promotes the conversion of testosterone to dihydrotestosterone and promotes the production of sebum and then free fatty acids.  Females with moderate to severe acne have zinc deficiency, compounded with elevated androgen activity (hyperandrogenism).

While we find little written material on androgen induced acne, practical experience has taught us it is more severe on the chin and along the jaw-line.  Bacterial control and keeping the follicles open are important aspects of treatment, but two products become important in correcting zinc deficiency combined with controlling the over abundance of androgens. 

In the case of moderate to severe acne, Inhibiting Gel is important in correcting the skin's zinc content and down-regulating the conversion of testosterone to dihydrotestosterone, etc.   In mild, moderate and severe acne Green Tea Poultice is important for its zinc content and also the additional ingredients that block testosterone conversion.    

The Skintactix regimen may provide nearly total acne control with the exception of the beginning of the monthly cycle.  Going into this period be sure to use the Green Tea Poultice in the AM as well as the PM, as per the instructions. 

Extended Antibiotic Use: 
Research published in February 2004 by the University of Washington of 10,000 females found that females who had used antibiotics approximately 500 days or more over an 18 year period were twice as likely to contract breast cancer as females at large.  Previous studies have show frequent or extended used of antibiotics may be damaging to the body's immune system.  Long-term control or maintenance of acne with antibiotics may involve risks and may be less desirable than effective topical products, having no side effects.

Hormone Supplementation:
The development of adult onset acne following the initiation of hormone supplementation or significant modification of an existing program may be caused by the dosage.  Speak with your physician about this subject and modifying the dosage so it does not cause acne. 

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